Bloom Wellness Lounge is a Health & Wellness facility that focuses on weight loss, facials and massage therapy. “Thank you to Dr. Ward and her amazing staff - this little boutique of health is quite amazing.” “I found Bloom through Pure Barre La Costa, and got a Skinny Shot...what a difference I felt almost instantly!” “Within a few minutes I could feel a difference in my energy and mood which lasted for a whole week.”Epub 2012 Mar 16.O'Neil PM1, Smith SR, Weissman NJ, Fidler MC, Sanchez M, Zhang J, Raether B, Anderson CM, Shanahan WR.Author information1Weight Management Center, Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC, USA.AbstractThe BLOOM-DM (Behavioral Modification and Lorcaserin for Obesity and Overweight Management in Diabetes Mellitus) study evaluated efficacy and safety of lorcaserin for weight loss in patients with type 2 diabetes. Secondary objectives included evaluations of glycemic control, lipids, blood pressure, and quality of life.

This 1-year, randomized, placebo-controlled trial enrolled 604 patients 1:1:1 to placebo, lorcaserin 10 mg once daily (QD) or lorcaserin 10 mg twice daily (BID). Patients were treated with metformin, a sulfonylurea (SFU) or both; had glycated hemoglobin (HbA(1c)) 7-10%; were 18-65 years old; and had BMI 27-45 kg/m(2). Patients received diet and exercise counseling. Safety monitoring included serial echocardiograms. Mean (± SD) age was 52.7 ± 8.7; 60.5% were white, 20.9% were African American, and 13.8% were Hispanic. Battery Operated Christmas Lights NycMean (± SD) weight was 103.6 ± 17.8 kg; Bamboo Floor Installation EstimateBMI was 36.0 ± 4.5 kg/m(2). Stainless Steel Toilet Seat HardwareMost patients (91.7%) took metformin; 50.2% took a SFU.

More patients lost ≥5% body weight with lorcaserin BID (37.5%; P < 0.001) or lorcaserin QD (44.7%; P < 0.001) vs. placebo (16.1%; modified intent to treat (MITT)/last observation carried forward (LOCF)). Least square mean (± SEM) weight change was -4.5 ± 0.35% with lorcaserin BID and -5.0 ± 0.5% with lorcaserin QD vs. -1.5 ± 0.36% with placebo (P < 0.001 for each). HbA(1c) decreased 0.9 ± 0.06 with lorcaserin BID, 1.0 ± 0.09 with lorcaserin QD, and 0.4 ± 0.06 with placebo (P < 0.001 for each); fasting glucose decreased 27.4 ± 2.5 mg/dl, -28.4 ± 3.8 mg/dl, and 11.9 ± 2.5 mg/dl, respectively (P < 0.001 for each). Symptomatic hypoglycemia occurred in 7.4% of patients on lorcaserin BID, 10.5% on lorcaserin QD, and 6.3% on placebo. Common adverse events were headache, back pain, nasopharyngitis, and nausea. Lorcaserin was associated with significant weight loss and improvement in glycemic control in patients with type 2 diabetes.TRIAL REGISTRATION: ClinicalTrials.gov NCT00603291.

PMID: 22421927 DOI: 10.1038/oby.2012.66 [PubMed - indexed for MEDLINE] Publication TypesRandomized Controlled TrialMeSH TermsAdultAgedAnti-Obesity Agents/therapeutic useBenzazepines/pharmacologyBenzazepines/therapeutic use*Blood Glucose/drug effectsBlood Glucose/metabolismBody Mass IndexCounselingDiabetes Mellitus, Type 2/bloodDiabetes Mellitus, Type 2/drug therapy*Double-Blind MethodEchocardiographyFemaleHemoglobin A, Glycosylated/drug effectsHemoglobin A, Glycosylated/metabolism*HumansHypoglycemic Agents/pharmacologyHypoglycemic Agents/therapeutic use*MaleMiddle AgedObesity/bloodObesity/drug therapy*Quality of LifeReceptor, Serotonin, 5-HT2C/drug effects*Risk Reduction BehaviorWeight Loss/drug effects*SubstancesAnti-Obesity AgentsBenzazepinesBlood GlucoseHemoglobin A, GlycosylatedHypoglycemic AgentsReceptor, Serotonin, 5-HT2Chemoglobin A1c protein, humanlorcaserinSecondary Source IDClinicalTrials.gov/NCT00603291Full Text SourcesWileyOther Literature SourcesSee the articles recommended by F1000Prime's Faculty of more than 5,000 expert scientists and clinical researchers.

- Faculty of 1000Cited by Patents in - The LensMedicalClinicalTrials.govDiabetes - Genetic AllianceDiabetes, Type 2 - Genetic AllianceDiabetes mellitus type 2 - Genetic AllianceA1C - MedlinePlus Health InformationDiabetes Medicines - MedlinePlus Health InformationDiabetes Type 2 - MedlinePlus Health InformationObesity - MedlinePlus Health InformationWeight Control - MedlinePlus Health InformationEnter your primary care doctor's name to find urgent care centers in your network. Enter your primary care doctor's name to find urgent care centers in your network. About Sharp Community Medical Group Enter your doctor's name to get office information. Enter your primary care doctor's name to find labs in your network. San Diego Weight Management Programs and SupportA healthy approach to successful weight loss. We know losing weight isn't easy — and finding a healthy method can be confusing. So at Sharp Rees-Stealy's Center for Health Management, we offer a variety of nonsurgical programs to help you lose weight safely.

Our expert teams teach practical skills for long-term success, and offer unwavering support for results you never thought possible. Choosing a program that works for you. As a patient at Sharp Rees-Stealy, you have access to dietitian consultations, telephonic health coaching and long-term support. Our Center for Health Management offers education programs, weight-loss kits and an online store stocked with healthy products. We have two structured, advanced programs to help you get the most out of your experience — Healthy Solutions® for learning principles of weight loss and a medically supervised program for those wanting extra guidance. And if your child's weight is worrying you, we offer the Healthy Kids, Healthy Habits program to help build the framework for a healthy future. Sharp Rees-Stealy Del Mar Weight Management and Health Education Sharp Rees-Stealy Mount Helix Weight Management and Health Education Sharp Rees-Stealy Murphy Canyon Weight Management and Health Education

Sharp Rees-Stealy Rancho Bernardo Weight Management and Health Education Experience our classes and webinars. HMR at Home: Weight-Loss Orientation Webinar Monday, Sept. 12, at 12 pm Monday, Sept. 19, at 12 pm See all available dates Choose the best doctor in San Diego for you. View doctors specializing in primary care in San Diego. "I am pleased to now be practicing at Sharp Rees-Stealy Rancho Bernardo where I believe high-quality health care is best achieved through strong patient-physician relationships and open communication." "I provide quality, personalized care focused on the best outcomes for each of my patients." "I have been in practice since 2006." "I enjoy working with people and assisting them in their time of need." Dr. Timothy H. Lee "Caring for patients is the greatest privilege." "I enjoy helping patients achieve their optimal health." "I have been in practice since 1976." "It is an honor to be a part of a health care organization that is committed to patient-centered care."